A U.S. study reports that drinking beverages sweetened with high fructose corn syrup (HFCS) is associated with an increased prevalence and risk of chronic bronchitis in American adults. Adults who drink non-diet soda five or more times per week are 1.8 times as likely to develop chronic bronchitis as people who drink them only once or twice a month. And it doesn’t matter if smoking is involved. The researchers suggested that poorly absorbed excess fructose in the gut interacts with proteins to form antigens (“enFruAGEs”) that work their way to the lungs, triggering an immune response and causing bronchitis. More research is needed to prove the connection.
"Intake of high fructose corn syrup sweetened soft drinks is associated with prevalent chronic bronchitis in U.S. Adults, ages 20–55 y", Nutrition Journal, October 16, 2015
New U.S. research in mice suggests that intestinal inflammation caused by a microbiome that lacks soluble fiber may be a key factor in obesity and in obesity-related diseases like diabetes. The researchers found that adding more soluble fiber to the diet restores the gut microbiome and intestinal health. For the study, researchers tested the effects of various diets (i.e., soluble and insoluble fiber, protein and fat) on the intestinal tracts of mice. Among other things, the researchers found that improvements in gut structure from a soluble fiber-rich diet were due to changes in the gut microbiota that produced anti-inflammatory molecules (short chain fatty acids) used as fuel by intestinal cells.
"Lack of soluble fiber drives diet-induced adiposity in mice. ", American Journal of Physiology - Gastrointestinal and Liver Physiology, November 13, 2015
Some studies have linked metabolic syndrome with the fermentation activities of bacteria on soluble fiber in the intestines. The bacteria digest the fiber, creating short chain fatty acids that control inflammation and reduce the risk of obesity. So it is usually healthful to increase fiber consumption. But a new U.S. study found a link between unchecked bacterial fermentation, increased short-chain fatty acids and increased liver lipids in people (and mice) with a compromised “TLR5” function. A defect in the TLR5 receptor reduces control of bacteria volumes. Bacteria multiply, lipids rise, as does the risk of non-alcoholic fatty liver disease and liver damage.
"Microbiota-Dependent Hepatic Lipogenesis Mediated by Stearoyl CoA Desaturase 1 (SCD1) Promotes Metabolic Syndrome in TLR5-Deficient Mice", Cell Metabolism, November 13, 2015
A small U.S. pilot study has determined that weight loss could be as simple a matter as counting – but not steps, or minutes of exercise, or calories. The 41 participants who completed the study counting bites as they ate lost about four pounds on average (a healthful pound per week). Participants also committed to taking 20 to 30 percent fewer bites over four weeks. They changed nothing else about their eating or exercising patterns. Those who didn’t finish the program blamed the difficulty of keeping count, so computer scientists developed an algorithm for that. The technology was licensed to a local Utah startup (SmartBites) that is working on an app for wearable devices such as Android Wear and WatchOS devices.
"Pilot Test of A Bites-Focused Weight Loss Intervention. ", Advances in Obesity, Weight Management & Control, November 13, 2015
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PLOS One, October 20, 2015
Nutrition Insight, October 23, 2015
The American Journal of Clinical Nutrition, October 28, 2015
Nutrition Journal, October 30, 2015
The American Journal of Clinical Nutrition, November 04, 2015
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