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A Person’s Diet Quality – Not Weight – Is Linked To Onset Of Type 2 Diabetes

September 17, 2014: 12:00 AM EST
A Danish study of genetically identical twins -- one heavier, one leaner -- finds that the onset of type 2 diabetes, usually associated with being overweight or obese, actually has more to do with the quality of the diet, not just the number of calories consumed. The twins ate the same fast food (Big Mac) meals, after which their blood and fecal microbiota were analyzed. The circulating metabolites, including those related to type 2 diabetes, were found in both individuals at the same levels, regardless of their weight. The researchers concluded that what people eat – not just the number of calories – may be the most important factor in people’s health.
I. Bondia-Pons et al., "Metabolome and fecal microbiota in monozygotic twin pairs discordant for weight: a Big Mac challenge. ", The FASEB Journal, September 17, 2014, © Federation of American Societies for Experimental Biology
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