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Abdominal Fat Linked To Increased Risk Of Colon Cancer

March 6, 2013: 12:00 AM EST
A U.S. study in mice shows that the risk of cancer is directly proportional to the amount of fat in the abdominal cavity. Scientists have known for some time that obesity boosts the risk of cancer. But in this study, researchers tested three groups of obese mice genetically engineered to be prone to colon cancer. They found that mice who were the most obese due to an unrestricted diet had the most visceral fat and the greatest number of intestinal tumors. When the visceral fat in some obese mice was removed surgically, the mice were still obese, but had significantly fewer tumors.
D. M. Huffman et al., "Abdominal Obesity, Independent from Caloric Intake, Accounts for the Development of Intestinal Tumors in Apc1638N/ Female Mice", Cancer Prevention Research, March 06, 2013, © American Association for Cancer Research
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