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Antibiotic Works Better Than Cranberry Capsules At Preventing UTI Recurrences

July 25, 2011: 09:28 AM EST
The standard antibiotic used to treat urinary tract infections (UTI) did a better job of preventing recurrences of the condition in premenopausal women than cranberry capsules, Dutch researchers have found. They warned, however, that low-dose antibiotics can contribute to antibiotic resistance over time. For the study, 221 women with symptoms of UTI took either 480 mg of trimethoprim-sulfamethoxazole (TMP-SMX) daily or 500 mg cranberry capsules twice daily. At 12 months, the average number of clinical recurrences OF UTI was 1.8 in the TMP-SMX group and 4.0 in the cranberry capsules group. However, antibiotic resistance rates tripled in the pathogens found in the TMP-SMX patients.
M. A. J. Beerepoot, et al. , "Cranberries vs Antibiotics to Prevent Urinary Tract Infections: A Randomized Double-blind Noninferiority Trial in Premenopausal Women", Archives of Internal Medicine, July 25, 2011, © American Medical Association
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