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Coenzyme Q10 Supplementation Affects Gene Expression, Reduces Cholesterol

January 28, 2011: 11:08 AM EST
A clinical study by German researchers has found that the vitamin-like compound coenzyme Q10 (CoQ10) induces gene expression patterns that affect inflammation and blood cell creation, and reduce LDL cholesterol levels. The two-week study involved 53 healthy males (average age 30) who took a reduced form of CoQ10  (ubiquinol, Q10H2, 150 mg/d). Blood tests indicated that LDL (“bad cholesterol”) levels dropped as CoQ10 levels increased. “Q10H2 induces characteristic gene expression patterns, which are translated into reduced LDL cholesterol levels and altered parameters of erythropoiesis (i.e., red blood cell formation) in humans,” the researchers concluded.
C. Schmelzer, et al. , "Ubiquinol-Induced Gene Expression Signatures are Translated into Altered Parameters of Erythropoiesis and Reduced Low Density Lipoprotein Cholesterol Levels in Humans", IUBMB Life, January 28, 2011, © Wiley Periodicals, Inc.
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