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Fructose Found To Be The Culprit When Obese People Develop Fatty Liver Disease

May 2, 2012: 12:00 AM EST
U.S. researchers have found out why consuming high levels of fructose – the sugar found most often in soft drinks and fruit juices – often leads to dangerous nonalcoholic fatty liver disease in obese people. Consuming too much fructose on a regular basis depletes the store of ATP, a molecule that provides liver and other body cells with energy for important cellular processes, including metabolism. When liver cells are unable to generate cellular energy because of ATP depletion, the risk for inflammation and scarring in the liver increases.
Manal F. Abdelmalek et al., "Higher dietary fructose is associated with impaired hepatic ATP homeostasis in obese individuals with type 2 diabetes", Hepatology, May 02, 2012, © John Wiley & Sons, Inc.
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