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Glucose And Fructose Have Same Metabolic Impact, So Substitution Would Be Pointless

January 31, 2014: 12:00 AM EST
Canadian researchers report in a review of earlier studies that there’s really no difference between fructose and glucose on human metabolism. Fructose, often in the form of high fructose corn syrup, is used extensively in processed foods, and has been blamed for contributing to the obesity epidemic. But when the researchers analyzed the scientific literature, they found that consuming fructose does increase total cholesterol and triglyceride fats found in blood after eating a meal. But it does not appear to affect insulin production, other fat levels in the blood, or markers of fatty liver disease any more than glucose does. So there’s no point in substituting glucose for fructose in foods.
John L. Sievenpiper et al., "Fructose vs. glucose and metabolism", Current Opinion in Lipidology, January 31, 2014, © Wolters Kluwer Health
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