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High Folic Acid Intake Seems To Protect Against Colorectal Cancer

August 3, 2011: 12:54 PM EST
U.S. scientists who analyzed diet data on more than half a million Americans aged 50 to 71 found that, contrary to some suggestions, high intake of dietary or supplemental folate does not increase the risk of colorectal cancer. In fact, a higher total intake of folate was associated with a significantly lower risk of colorectal cancer. The study was launched to determine whether mandatory folic acid fortification of grain products might lead to adverse health consequences. It included more than eight years of follow-up data. However, the researchers suggested that because “the adenoma-carcinoma sequence” may take longer than ten years, more follow-up time is necessary.
T.M. Gibson, et al. , "Pre- and postfortification intake of folate and risk of colorectal cancer in a large prospective cohort study in the United States", American Journal of Clinical Nutrition, August 03, 2011, © American Society for Nutrition
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