Korean Plant Found To Inhibit Osteoporosis, Induce Bone Tissue Growth

An extract of the edible Korean plant trifoliate orange (P. trifoliate) was found to inhibit glucocortiod-induced osteoporosis (GIO) and to promote bone tissue formation in a study in mice. The Korean researchers suggested that the molecular mechanism behind the inhibitory effect may be due to decreased expression of the gene AnxA6. All in all, researchers tested 68 ethanol or methanol extracts of edible Korean plants. “These findings suggest that [trifoliate orange] has a strong in vitro  and in vivo inhibitory effect on GIO, and decreased expression of AnxA6 may play a key role in this inhibition,” the researchers concluded.