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“Natural” Stimulant Found In Nutritional Supplements Is Actually Synthetic – And Dangerous

July 12, 2012: 12:00 AM EST
A substance known as DMAA (1,3-dimethylamylamine), which is marketed as a “natural” stimulant in a variety of pre-workout and nutritional supplements, is actually a synthetic compound, U.S. researchers have found. Some DMAA products claim the compound is derived from geranium plants. But the deaths of two U.S. soldiers after using DMAA-based supplements led to closer scrutiny. Investigators not only found no DMAA in geranium plants, they determined that DMAA comprises four synthetic compounds called stereo-isomers. They recommended that the FDA either regulate or ban “products in which significant amounts of pharmacological compounds are added.”
Ying Zhang et al., "1,3-Dimethylamylamine (DMAA) in supplements and geranium products: natural or synthetic?", Drug Testing and Analysis, July 12, 2012, © John Wiley & Sons, Ltd.
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