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Obesity Factor in Ovarian Cancer

January 5, 2009: 04:56 PM EST
Obese women who have never used menopausal hormone therapy are at higher risk of developing ovarian cancer than similar women of normal weight. The mechanism is thought to be hormonal. The finding comes from a review by a team led by Dr Michael F. Leitzmann of the National Cancer Institute of data from nearly 95,000 women aged 50 to 71, 303 of whom had ovarian cancer. Obesity was associated with an 80 percent increase in the risk of the disease among women who had not taken hormones after menopause. There was no link between the cancer and woman who had ever used hormones. Overweight postmenopausal women produce more estrogen, which may stimulate the growth of ovarian cells and play a role in the development of ovarian cancer. The risk was also higher in overweight postmenopausal women with no family history of ovarian cancer.
"Study Links Obesity to Elevated Risk of Ovarian Cancer", Nutrition Horizon , January 05, 2009, © CNS Media BV
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