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Prevention Of Type 2 Diabetes May Begin In The Womb With Healthy Nutrition

January 6, 2012: 12:00 AM EST
Potential new preventative treatments for type 2 diabetes may begin as early as pre-birth, according to British research. Poor nutrition in the womb can put a person at greater risk of developing type 2 diabetes and other age-related diseases because they are less able to store fats correctly as adults. Storing fats in the right areas of the body is important because otherwise they can accumulate in places like the liver and muscle where they are more likely to lead to disease. The process is controlled by a molecule called miR-483-3p produced at higher levels in individuals who had experienced a poor diet in their mother's wombs than those who were better nourished.
D. Ferland-McCollough et al., "Programming of adipose tissue miR-483-3p and GDF-3 expression by maternal diet in type 2 diabetes", Cell Death and Differentiation, January 06, 2012, © Associazione Differenziamento e Morte Cellulare
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