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Strict Control Of Glucose Levels In Diabetics Prevents Neuropathy – But With Serious Side Effects

June 13, 2012: 12:00 AM EST
Half of diabetics develop a disabling condition known as diabetic neuropathy, which leaves feet and legs feeling tingly, numb, painful or weak. Neuropathy can be prevented by strict control of blood sugar levels. But a U.S. and British review of six clinical studies of enhanced glucose control methods – extra insulin injections, anti-diabetic drugs, and diet changes – has found that they can be effective, there is a significant risk of adverse effects, including hypoglycemia. Further research is needed to find optimum target levels for safe treatments that will both prevent neuropathy and minimize serious side effects, according to the scientists who conducted the review.
Brian C Callaghan et al., "Enhanced glucose control for preventing and treating diabetic neuropathy", Cochrane Review, June 13, 2012, © John Wiley & Sons, Inc.
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