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Synthetic Compounds In Fish Oil Capsules Do Not Reduce Inflammation

August 19, 2015: 12:00 AM EST
Compounds known as resolvins, maresins and protectins formed from oily fish have been shown to reduce inflammation. Synthetic versions of the compounds have been tested successfully in lab dishes and in animals. But a new U.S. study comparing synthetic fish oil compounds found in supplements to those naturally occurring in fish finds that the synthetic versions are not nearly as absorbable or digestible by the human gut as natural versions. That means they are less likely to offer any anti-inflammatory benefits that would reduce the risk of heart disease. After rigorous testing, the researchers “found no evidence” that fish oil capsules play any role in reducing inflammation.
Carsten Skarke et al., "Bioactive products formed in humans from fish oils. ", Journal of Lipid Research, August 19, 2015, © The American Society for Biochemistry and Molecular Biology
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