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The Type Of Selenium Used To Treat Cancer Is Critical To Success

January 24, 2011: 10:35 AM EST
Researchers in two earlier clinical trials that used selenium to fight cancer came up with conflicting results: one showed that selenium reduced cancer risk, while the other showed no beneficial effect at all. But U.S. and Australian scientists may have found a reason for the discrepancy in the results of the trials: the types of selenium used in the two studies were different. For the new study, the researchers analyzed how two forms of selenium – SeMet and MeSeCys – are processed in human lung cancer cells. MeSeCys killed more lung cancer cells than SeMet, and the cells treated with MeSeCys processed the selenium differently than cells treated with SeMet.
Claire M. Weekley, et al. , "Uptake, Distribution, and Speciation of Selenoamino Acids by Human Cancer Cells: X-ray Absorption and Fluorescence Methods", Biochemistry, January 24, 2011, © American Chemical Society
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