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Usually Beneficial Resveratrol Worsens Symptoms In MS Mice

October 1, 2013: 12:00 AM EST
Numerous animal studies of the polyphenol resveratrol, found in the skin of red grapes and in red wine, have demonstrated its anti-inflammatory and antioxidant properties. But a new U.S. study in animal models of multiple sclerosis finds that resveratrol exacerbates MS-like neuropathology and inflammation, and has no neuroprotective effects. The findings were so significant in the lab mice that the lead researcher said resveratrol “should be discouraged for supplemental use by MS patients pending further research".
Fumitaka Sato et al., "Resveratrol Exacerbates Both Autoimmune and Viral Models of Multiple Sclerosis", The American Journal of Pathology, October 01, 2013, © The American Journal of Pathology
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