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Vitamin D Supplementation Does Not Lower Cholesterol

August 31, 2012: 12:00 AM EST
Researchers who studied people with vitamin D deficiency taking large doses (50,000 IU) of vitamin D3 for eight weeks found no decrease in cholesterol levels of the participants. Vitamin D therapy did result in decreased parathyroid hormone levels and increased calcium levels, changes that were linked to an increase in low-density lipoprotein (LDL, bad cholesterol). The U.S. researchers recommended longer-term studies on the impact of the changes in LDL cholesterol with vitamin D therapy. They also wondered whether exposure to sunlight, the predominant natural source of vitamin D, would have a different effect than supplements.
Manish P. Ponda et al., "The Short-Term Effects of Vitamin D Repletion on Cholesterol: A Randomized, Placebo-Controlled Trial", Arteriosclerosis, Thrombosis and Vascular Biology, August 31, 2012, © American Heart Association, Inc.
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