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Wonder Drug Dupes The Body Into Burning Fat

January 9, 2015: 12:00 AM EST
A multinational team of researchers has developed a drug that – in preclinical testing – stops weight gain, spurs fat burning, lowers cholesterol, controls blood sugar and minimizes inflammation. According to the scientists from the Salk Institute of Biological Studies, fexaramine is unlike appetite suppressants or caffeine-based diet drugs because it doesn’t dissolve in the blood. It remains in the intestines, acting like an “imaginary meal”. Fexaramine emits the same signals that the body sends out after a heavy meal, “so the body starts clearing out space to store it”. The body thinks it has consumed calories, though it hasn’t, and it starts burning fat, without side effects. Clinical trials are the next step, the scientists say.
Sungsoon Fang et al., "Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance. ", Nature Medicine, January 09, 2015, © Macmillan Publishers Limited
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